Sort1^tm1Xen
Targeted Allele Detail

Summary

• Symbol: Sort1^tm1Xen
• Name: sortilin 1; targeted mutation 1, Taconic Biosciences
• MGI ID: MGI:5824300
• Gene: Sort1 Location: Chr3:108191398-108268827 bp, + strand Genetic Position: Chr3, 46.9 cM, cytoband F3
• Alliance: Sort1^tm1Xen page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:238484
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Insertion
• A stop codon was inserted into intron 2. (J:238484)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Sort1 Mutation: 47 strains or lines available

References

• Original: J:238484 Li J, et al., Sortilin 1 Modulates Hepatic Cholesterol Lipotoxicity in Mice via Functional Interaction with Liver Carboxylesterase 1. J Biol Chem. 2017 Jan 06;292(1):146-160
• All: 2 reference(s)