Cpt2^tm1Mwol
Targeted Allele Detail

Summary

• Symbol: Cpt2^tm1Mwol
• Name: carnitine palmitoyltransferase 2; targeted mutation 1, Michael J Wolfgang
• MGI ID: MGI:5819280
• Gene: Cpt2 Location: Chr4:107761179-107780786 bp, - strand Genetic Position: Chr4, 50.18 cM
• Alliance: Cpt2^tm1Mwol page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:222812
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: C57BL/6

Mutation description

• Allele Type: Targeted (Conditional ready)
• Mutation: Insertion
• LoxP sequences were inserted into the introns flanking exon 4 of the gene. (J:222812)

Expression

In Mice Carrying this Mutation:	5 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation:	2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Cpt2 Mutation: 28 strains or lines available

References

• Original: J:222812 Lee J, et al., Adipose fatty acid oxidation is required for thermogenesis and potentiates oxidative stress-induced inflammation. Cell Rep. 2015 Jan 13;10(2):266-79
• All: 22 reference(s)