Arhgap44^em1(IMPC)J
Endonuclease-mediated Allele Detail

Summary

• Symbol: Arhgap44^em1(IMPC)J
• Name: Rho GTPase activating protein 44; endonuclease-mediated mutation 1, Jackson
• MGI ID: MGI:5806663
• Synonyms: Arhgap44^em1J
• Gene: Arhgap44 Location: Chr11:64892865-65053779 bp, - strand Genetic Position: Chr11, 40.42 cM
• Alliance: Arhgap44^em1(IMPC)J page
• IMPC: Arhgap44 gene page

Mutation origin

• Strain of Origin: C57BL/6NJ
• Project Collection: IMPC

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: This allele was generated at The Jackson Laboratory using Cas9 and guides with spacer sequences ACTTAGTACAAGCACACACA, ATAGTTTACTAATATAACTG, CCTAGACCCTGACTGCAGAT, and GCGGGTGGAAGATTTTCAGT that targeted exon(s) ENSMUSE00000589381.2. This resulted in deletion(s) of 5 bp (location: Chr11:64958077-64958081; GRCm39), 12 bp (location: Chr11:64957848-64957859; GRCm39), 14 bp (location: Chr11:64958004-64958017; GRCm39), and 88 bp (location: Chr11:64957886-64957973; GRCm39). This description was generated automatically. Additional molecular information including FASTA sequence support for this allele can be found here: (IMPC Gene page) and viewed in a genome context here: (IMPC Genome Browser). (J:384794)

• Inheritance: Not Specified

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Arhgap44 Mutation: 36 strains or lines available

References

• Original: J:188991 The Jackson Laboratory, Alleles produced for the KOMP project by The Jackson Laboratory. MGI Direct Data Submission. 2012
• All: 4 reference(s)