Anks1b^tm1Bnaj
Targeted Allele Detail

Summary

• Symbol: Anks1b^tm1Bnaj
• Name: ankyrin repeat and sterile alpha motif domain containing 1B; targeted mutation 1, Bryen A Jordan
• MGI ID: MGI:5779292
• Synonyms: AIDA-1^fl
• Gene: Anks1b Location: Chr10:89709371-90809162 bp, + strand Genetic Position: Chr10, 45.28 cM
• Alliance: Anks1b^tm1Bnaj page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:222552
• Parent Cell Line: iTL BA1 (ES Cell)
• Strain of Origin: (C57BL/6NTac x 129S6/SvEvTac)F1

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: A loxP site was inserted upstream of exon 20 (formerly designated exon 7). An FRT-flanked neomycin resistance cassette with a 3' loxP site was inserted downstream of exon 20. (J:222552)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Anks1b Mutation: 52 strains or lines available

References

• Original: J:222552 Tindi JO, et al., ANKS1B Gene Product AIDA-1 Controls Hippocampal Synaptic Transmission by Regulating GluN2B Subunit Localization. J Neurosci. 2015 Jun 17;35(24):8986-96
• All: 3 reference(s)