Htr1b^{tm3.1(tetO-Htr1b)Rhn}
Targeted Allele Detail

Summary

• Symbol: Htr1b^{tm3.1(tetO-Htr1b)Rhn}
• Name: 5-hydroxytryptamine (serotonin) receptor 1B; targeted mutation 3.1, Rene Hen
• MGI ID: MGI:5752473
• Synonyms: tetO1B
• Gene: Htr1b Location: Chr9:81510344-81515881 bp, - strand Genetic Position: Chr9, 44.61 cM
• Alliance: Htr1b^{tm3.1(tetO-Htr1b)Rhn} page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:221569
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129S6/SvEv

Mutation description

• Allele Type: Targeted (Conditional ready, Inducible, Inserted expressed sequence)
• Inducer: doxycycline/tetracycline
• Mutations: Insertion, Intragenic deletion
• Htr1b^{tm3.1(tetO-Htr1b)Rhn} expresses 1 gene
  Knock-in expresses:
  

  Organism	Expressed Gene	Note
  Not Specified	Htr1b

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Htr1b Mutation: 26 strains or lines available

References

• Original: J:221569 Nautiyal KM, et al., Distinct Circuits Underlie the Effects of 5-HT1B Receptors on Aggression and Impulsivity. Neuron. 2015 May 6;86(3):813-26
• All: 3 reference(s)