Cdh23^ahl+em2H
Endonuclease-mediated Allele Detail

Summary

• Symbol: Cdh23^ahl+em2H
• Name: cadherin related 23 (otocadherin); endonuclease-mediated revertant 2, Harwell
• MGI ID: MGI:5750023
• Synonyms: Cdh23^em2H
• Gene: Cdh23 Location: Chr10:60138527-60532269 bp, - strand Genetic Position: Chr10, 30.11 cM
• Alliance: Cdh23^ahl+em2H page
• IMPC: Cdh23 gene page

Mutation origin

• Strain of Origin: C57BL/6NTac
• Project Collection: IMPC

Mutation description

• Allele Type: Endonuclease-mediated (Not Specified)
• Mutations: Intragenic deletion, Nucleotide substitutions
• Mutation details: CRISPR endonuclease-mediated technology was used to repair the mutation observed in mice with Cdh23^ahl allele (c.753A>G). This allele also contains a 24 nucleotide in-frame deletion within the gene. (J:90559, J:236297)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Cdh23 Mutation: 275 strains or lines available

References

• Original: J:90559 The Mammalian Genetics Unit at Harwell, Information obtained from the Mammalian Genetics Unit, Medical Research Council (MRC), Harwell, UK. Unpublished. 2004-2013
• All: 4 reference(s)