Tbbr3^BALB/c
QTL Variant Detail

Summary

• QTL variant: Tbbr3^BALB/c
• Name: Trypanosoma brucei brucei response 3; BALB/c
• MGI ID: MGI:5749555
• QTL: Tbbr3 Location: Chr7:117750722-117750843 bp Genetic Position: Chr7, Syntenic

Variant origin

• Strain of Specimen: BALB/c

Variant description

• Allele Type: QTL

Notes

F2 mice with homozygous BALB/c (CC) alleles at Tbbr3 and STS/A (SS) alleles at Tbbr4 or homozygous STS/S (SS) alleles at Tbbr3 and homozygous BALB/c (CC) alleles at Tbbr4 have a shorter survival time after infection in comparison with other possible allelic combinations at these 2 loci.

References

• Original: J:179355 Sima M, et al., Genetic control of resistance to Trypanosoma brucei brucei infection in mice. PLoS Negl Trop Dis. 2011 Jun;5(6):e1173
• All: 1 reference(s)