Fgfrl1^tm2.1True
Targeted Allele Detail

Summary

• Symbol: Fgfrl1^tm2.1True
• Name: fibroblast growth factor receptor-like 1; targeted mutation 2.1, Beat Trueb
• MGI ID: MGI:5707709
• Synonyms: FgfrL1deltaC-GFP
• Gene: Fgfrl1 Location: Chr5:108842051-108854816 bp, + strand Genetic Position: Chr5, 53.24 cM, cytoband E3-F
• Alliance: Fgfrl1^tm2.1True page

Morphology of kidneys in heterozygous and homozygous Fgfrl1^tm2.1True mice

Show the 3 phenotype image(s) involving this allele.

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:218981
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: C57BL/6 x 129S/SvEv

Mutation description

Allele Type: Targeted (Reporter) Mutations: Insertion, Intragenic deletion Mutation details: The region of exon 7 which codes for three conserved motifs of the intracellular domain (amino acids 441-529) was replaced by an in-frame GFP reporter sequence. Flp-mediated recombination removed the FRT-flanked neomycin resistance cassette inserted downstream of the modified exon 7. (J:218981)

Generation of the Fgfrl1^tm2.1True allele

Expression

In Mice Carrying this Mutation:

1 RNA-Seq or microarray experiment(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Fgfrl1 Mutation: 28 strains or lines available

References

• Original: J:218981 Bluteau G, et al., Targeted disruption of the intracellular domain of receptor FgfrL1 in mice. PLoS One. 2014;9(8):e105210
• All: 1 reference(s)