Ube2j1^tm1.1Hpl
Targeted Allele Detail

Summary

• Symbol: Ube2j1^tm1.1Hpl
• Name: ubiquitin-conjugating enzyme E2J 1; targeted mutation 1.1, Hidde Ploegh
• MGI ID: MGI:5707496
• Synonyms: UBC6e^fl, Ube2j1^fl
• Gene: Ube2j1 Location: Chr4:33031416-33052363 bp, + strand Genetic Position: Chr4, 14.61 cM, cytoband A5
• Alliance: Ube2j1^tm1.1Hpl page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:218292
• Parent Cell Line: JM8A3.N1 (ES Cell)
• Strain of Origin: C57BL/6N-A^tm1Brd

Mutation description

Allele Type: Targeted (Conditional ready) Mutation: Insertion Mutation details: A loxP site was inserted upstream of exon 2 and an FRT flanked neo cassette and loxP site were inserted downstream of exon 3 via homologous recombination. Flp mediated recombination removed the neo cassette. (J:218292)

Generation of the Ube2j1^tm1.1Hpl and Ube2j1^tm1.2Hpl alleles

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Ube2j1 Mutation: 21 strains or lines available

References

• Original: J:218292 Koenig PA, et al., The E2 ubiquitin-conjugating enzyme UBE2J1 is required for spermiogenesis in mice. J Biol Chem. 2014 Dec 12;289(50):34490-502
• All: 2 reference(s)