Pcdh15^roda
Chemically induced Allele Detail

Summary

• Symbol: Pcdh15^roda
• Name: protocadherin 15; rodador
• MGI ID: MGI:5704141
• Gene: Pcdh15 Location: Chr10:72935174-74485569 bp, + strand Genetic Position: Chr10, 37.43 cM
• Alliance: Pcdh15^roda page

Mutation origin

• Strain of Origin: BALB/c

Mutation description

• Allele Type: Chemically induced (ENU)
• Mutation: Single point mutation
• Mutation details: ENU mutagenesis induced an A to G transition in intron 23, creating a novel intronic acceptor splice site. The truncated product lacks two cadherin domains, and the transmembrane and cytoplasmic domains.
• Inheritance: Recessive

Disease models

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Pcdh15 Mutation: 132 strains or lines available

Notes

This allele may be associated with Cdh23.

References

• Original: J:227974 Massironi SM, et al., Inducing mutations in the mouse genome with the chemical mutagen ethylnitrosourea. Braz J Med Biol Res. 2006 Sep;39(9):1217-26
• All: 2 reference(s)