Clu^{tm2(EGFP/cre/ERT2)Wtsi}
Targeted Allele Detail

Summary

• Symbol: Clu^{tm2(EGFP/cre/ERT2)Wtsi}
• Name: clusterin; targeted mutation 2, Wellcome Trust Sanger Institute
• MGI ID: MGI:5697395
• Gene: Clu Location: Chr14:66205932-66218996 bp, + strand Genetic Position: Chr14, 34.36 cM
• Alliance: Clu^{tm2(EGFP/cre/ERT2)Wtsi} page

Mutation origin

• Mutant Cell Line: CEPD0103_4_F04
• Germline Transmission: Earliest citation of germline transmission: J:188991
• Parent Cell Line: JM8.N4 (ES Cell)
• Strain of Origin: C57BL/6N
• Project Collection: EUCOMMTOOLS

Mutation description

• Allele Type: Targeted (Conditional ready, Inducible, Recombinase, Reporter)
• Inducer: tamoxifen
• Mutation: Insertion
• Clu^{tm2(EGFP/cre/ERT2)Wtsi} expression driven by 1 gene
  Knock-in expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Clu (MGI:88423)

• Mutation details: According to the allele molecular image presented by the International Knockout Mouse Consortium, this allele has a loxP site inserted into the intron between exons 5 and 6, and a cassette containing an FRT site followed by an engrailed 2 splice acceptor sequence, an EGFP and cre/ERT2 expression cassette, and a neomycin resistance cassette inserted into the intron between exons 3 and 4. (J:188991)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Clu (mouse) Summary of all recombinase alleles driven by Clu. Comparative matrix view of recombinase activities Alliance mouse Clu gene page

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Clu Mutation: 31 strains or lines available

References

• Original: J:188991 The Jackson Laboratory, Alleles produced for the KOMP project by The Jackson Laboratory. MGI Direct Data Submission. 2012
• All: 1 reference(s)