Cmv4^BALB/c
QTL Variant Detail

Summary

• QTL variant: Cmv4^BALB/c
• Name: cytomegalovirus resistance 4; BALB/c
• MGI ID: MGI:5693606
• QTL: Cmv4 Location: Chr6:127815180-136022150 bp Genetic Position: Chr6, cM position of peak correlated region/allele: 62.56 cM
• QTL Note: genome coordinates based on the boundaries of the QTL region

Variant origin

• Strain of Specimen: BALB/c

Variant description

• Allele Type: QTL
• Inheritance: Not Specified

Notes

Mapping and Phenotype information for this QTL, its variants and associated markers

J:108096

Cmv4 was mapped to a region of mouse Chromosome 6 between D6Mit52 and D6Mit301. Cmv49 exhibed a lod score of 21.9 with the Klra (Ly49e) region. The resistnce allele was found in PWK/Pas mice. Authors state in the discussion that they are unsure which locus (Nkrp, Clr, Nkg2 or Ly49) that the Cmv4 resistence in PWK/Pas is associated with.

References

• Original: J:108096 Adam SG, et al., Cmv4, a new locus linked to the NK cell gene complex, controls innate resistance to cytomegalovirus in wild-derived mice. J Immunol. 2006 May 1;176(9):5478-85
• All: 1 reference(s)