Taar1^m1J
Spontaneous Allele Detail

Summary

• Symbol: Taar1^m1J
• Name: trace amine-associated receptor 1; mutation 1, Jackson
• MGI ID: MGI:5688955
• Gene: Taar1 Location: Chr10:23796304-23797302 bp, + strand Genetic Position: Chr10, 11.39 cM, cytoband A3
• Alliance: Taar1^m1J page

Mutation origin

• Strain of Origin: DBA/2J

Mutation description

• Allele Type: Spontaneous (Hypomorph)
• Mutation: Single point mutation
• Mutation details: SNP rs33645709, a spontaneously arising C-to-A point mutation identified in DBA/2J, causes a proline to threonine mutation at amino acid position 77 (p.P77T) in the second transmembrane domain near the cytoplasmic side. (J:224677)
• Inheritance: Recessive

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 4 strains available Cell Lines: 0 lines available
• Carrying any Taar1 Mutation: 32 strains or lines available

References

• Original: J:224677 Harkness JH, et al., Trace Amine-Associated Receptor 1 Regulation of Methamphetamine Intake and Related Traits. Neuropsychopharmacology. 2015 Aug;40(9):2175-84
• All: 3 reference(s)