Tfcp2l1^tm1.1Bara
Targeted Allele Detail

Summary

• Symbol: Tfcp2l1^tm1.1Bara
• Name: transcription factor CP2-like 1; targeted mutation 1.1, Jonathan Barasch
• MGI ID: MGI:5645263
• Synonyms: Tcfcp2l1^loxP
• Gene: Tfcp2l1 Location: Chr1:118555675-118612898 bp, + strand Genetic Position: Chr1, 52.14 cM, cytoband E2
• Alliance: Tfcp2l1^tm1.1Bara page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:213786
• Parent Cell Line: KV1 (ES Cell)
• Strain of Origin: (C57BL/6J x 129S6/SvEvTac)F1

Mutation description

• Allele Type: Targeted (Conditional ready)
• Mutation: Insertion
• Mutation details: Exons 3-5 were floxed by inserting a floxed neo cassette and an FRT flanked neo cassette with a single loxP site via BAC recombineering. Both selection cassettes were removed by recombinase mediated recombination. (J:213786)

Expression

In Mice Carrying this Mutation:

1 RNA-Seq or microarray experiment(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Tfcp2l1 Mutation: 101 strains or lines available

References

• Original: J:213786 Paragas N, et al., alpha-Intercalated cells defend the urinary system from bacterial infection. J Clin Invest. 2014 Jul 1;124(7):2963-76
• All: 3 reference(s)