Tg(CAG-RFP/EGFP/Map1lc3b)1Hill
Transgene Detail

Summary

• Symbol: Tg(CAG-RFP/EGFP/Map1lc3b)1Hill
• Name: transgene insertion 1, Joseph Hill
• MGI ID: MGI:5635828
• Synonyms: CAG-RFP-EGFP-LC3
• Transgene: Tg(CAG-RFP/EGFP/Map1lc3b)1Hill Location: unknown
• Alliance: Tg(CAG-RFP/EGFP/Map1lc3b)1Hill page

Transgene origin

• Strain of Origin: C57BL/6

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence, Reporter)
• Mutation: Insertion
• Tg(CAG-RFP/EGFP/Map1lc3b)1Hill expresses 1 gene
  Transgene expresses:
  

  Organism

  Expressed Gene

  Homolog in Mouse

  Note

  rat

  Map1lc3b (64862)

  Map1lc3b

  (MGI:1914693)

  Fused with RFP and GFP

• Mutation details: The transgene was designed with a human cytomegalovirus immediate early promoter enhancer with chicken beta-actin/rabbit beta-globin hybrid promoter (CAG; from the pCAGGS vector) driving expression of a fusion of a red fluorescent protein (RFP) with a Strep-tag sequence to facilitate isolation, an enhanced green fluorescent protein (EGFP), and a microtubule-associated protein 1 light chain 3 beta (Map1lc3b or LC3) gene. (J:220669)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available

References

• Original: J:220669 Li L, et al., New autophagy reporter mice reveal dynamics of proximal tubular autophagy. J Am Soc Nephrol. 2014 Feb;25(2):305-15
• All: 25 reference(s)