Ffar4^tm1.1Mbj
Targeted Allele Detail

Summary

• Symbol: Ffar4^tm1.1Mbj
• Name: free fatty acid receptor 4; targeted mutation 1.1, Mikael Bjursell
• MGI ID: MGI:5635615
• Synonyms: Gpr120 KO/KI
• Gene: Ffar4 Location: Chr19:38085527-38102711 bp, + strand Genetic Position: Chr19, 32.73 cM
• Alliance: Ffar4^tm1.1Mbj page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:211675
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutations: Insertion, Intragenic deletion
• Mutation details: A nuclear lacZ expression and floxed neomycin resistance cassette replaced 0.567 kb of exon 1. Cre-mediated recombination removed the selection cassette. (J:211675)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Ffar4 Mutation: 23 strains or lines available

References

• Original: J:211675 Stone VM, et al., GPR120 (FFAR4) is preferentially expressed in pancreatic delta cells and regulates somatostatin secretion from murine islets of Langerhans. Diabetologia. 2014 Jun;57(6):1182-91
• All: 4 reference(s)