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Targeted Allele Detail
Symbol: S1pr2tm1.1Toka
Name: sphingosine-1-phosphate receptor 2; targeted mutation 1.1, Takaharu Okada
MGI ID: MGI:5605543
Synonyms: S1pr2V, S1pr2Venus
Gene: S1pr2  Location: Chr9:20877248-20888089 bp, - strand  Genetic Position: Chr9, 7.68 cM
Alliance: S1pr2tm1.1Toka page
Germline Transmission:  Earliest citation of germline transmission: J:214445
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  C57BL/6J x C57BL/6N
Allele Type:    Targeted (Reporter)
Mutations:    Insertion, Intragenic deletion
Mutation detailsThe first 498 bp of S1pr2 protein coding region was replaced with a yellow fluorescent protein (Venus) gene. A loxP-flanked PGK-Neo cassette that was inserted before exon 2 was removed via Cre-mediated recombination. (J:214445)
View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any S1pr2 Mutation:  43 strains or lines available
Original:  J:214445 Moriyama S, et al., Sphingosine-1-phosphate receptor 2 is critical for follicular helper T cell retention in germinal centers. J Exp Med. 2014 Jun 30;211(7):1297-305
All:  4 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
MGI 6.22
The Jackson Laboratory