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Angpt1tm1.1Yona
Targeted Allele Detail
Summary
Symbol: Angpt1tm1.1Yona
Name: angiopoietin 1; targeted mutation 1.1, Yoshikazu Nakaoka
MGI ID: MGI:5585457
Synonyms: Ang1fl, Ang1flox
Gene: Angpt1  Location: Chr15:42288119-42540373 bp, - strand  Genetic Position: Chr15, 16.69 cM
Alliance: Angpt1tm1.1Yona page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:213456
Parent Cell Line:  TT2 (ES Cell)
Strain of Origin:  (C57BL/6NCrlj x CBA/JNCrlj)F1
Mutation
description
Allele Type:    Targeted (Conditional ready, No functional change)
Mutation:    Insertion
 
Mutation detailsExon 1 was floxed. Flp-mediated recombination removed the FRT-flanked neomycin resistance cassette inserted downstream of exon 1. (J:213456, J:288357)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 4 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Angpt1 Mutation:  35 strains or lines available
References
Original:  J:213456 Lee J, et al., Angiopoietin-1 guides directional angiogenesis through integrin alphavbeta5 signaling for recovery of ischemic retinopathy. Sci Transl Med. 2013 Sep 18;5(203):203ra127
All:  10 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/07/2024
MGI 6.23
The Jackson Laboratory