Del(16Ifnar1-Kcnj6)11Yey
Targeted Allele Detail

Summary

• Symbol: Del(16Ifnar1-Kcnj6)11Yey
• Name: deletion, Chr 16, Y Eugene Yu 11
• MGI ID: MGI:5561091
• Synonyms: Del11Yey, Del(16Ifnar1-Kcnj6)Yey, Df(16)4Yey, Df(16Ifnar1-Kcnj6)Yey, Ms5Yey
• Gene: Del(16Ifnar1-Kcnj6)11Yey Location: unknown Genetic Position: Chr16, Syntenic

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:208104
• Parent Cell Line: AB2.2 (ES Cell)
• Strain of Origin: 129S7/SvEvBrd-Hprt1^b-m2

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intergenic deletion, Intragenic deletion
• Del(16Ifnar1-Kcnj6)11Yey involves 87 genes/genome features (Gm23062, Gm22745, Gm22344 ...) View all
• Mutation details: This deletion was generated by recombination between two MICER clone insertions (MHPn247l16 and MHPP54c08). The 3.7 Mb deletion spans Ifnar1 to Kcnj6, which contains 17 Hsa21 gene orthologs. The tyrosinase and Agouti transgenes from the MICER clones remain. (J:208104)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Del(16Ifnar1-Kcnj6)11Yey Mutation: 0 strains or lines available

References

• Original: J:208104 Liu C, et al., Engineered chromosome-based genetic mapping establishes a 3.7 Mb critical genomic region for Down syndrome-associated heart defects in mice. Hum Genet. 2014 Jun;133(6):743-53
• All: 1 reference(s)