About   Help   FAQ
Targeted Allele Detail
Symbol: Gtf2itm1Vcam
Name: general transcription factor II I; targeted mutation 1, Victoria Campuzano
MGI ID: MGI:5532204
Synonyms: Gtf2ideltaexon2
Gene: Gtf2i  Location: Chr5:134266688-134343614 bp, - strand  Genetic Position: Chr5, 74.48 cM
Alliance: Gtf2itm1Vcam page
Embryonic abnormalities and craniofacial dysmorphology in Gtf2itm1Vcam/Gtf2itm1Vcam mutant mice

Show the 1 phenotype image(s) involving this allele.

Germline Transmission:  Earliest citation of germline transmission: J:204278
Parent Cell Line:  R1 (ES Cell)
Strain of Origin:  (129X1/SvJ x 129S1/Sv)F1-Kitl+
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
Mutation detailsA lox511 site and neomycin resistance cassette replaced part of intron 1, exon 2, which contains the ATG translation initiation codon, and part of intron 2. (J:204278)
Generation of the Gtf2itm1Vcam allele
View phenotypes and curated references for all genotypes (concatenated display).
Disease models
In Structures Affected by this Mutation: 5 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Gtf2i Mutation:  109 strains or lines available
Original:  J:204278 Lucena J, et al., Essential role of the N-terminal region of TFII-I in viability and behavior. BMC Med Genet. 2010;11:61
All:  4 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
MGI 6.22
The Jackson Laboratory