Fermt2^tm2.1Ref
Targeted Allele Detail

Summary

• Symbol: Fermt2^tm2.1Ref
• Name: fermitin family member 2; targeted mutation 2.1, Reinhard Fassler
• MGI ID: MGI:5529148
• Synonyms: Fermt2^flox
• Gene: Fermt2 Location: Chr14:45696252-45767575 bp, - strand Genetic Position: Chr14, 22.97 cM
• Alliance: Fermt2^tm2.1Ref page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:185558
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Exon 15 was floxed. Flp-mediated recombination removed the selection cassette. (J:185558, J:230650)

Expression

In Mice Carrying this Mutation:

4 assay results

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Fermt2 Mutation: 32 strains or lines available

References

• Original: J:185558 Bottcher RT, et al., Sorting nexin 17 prevents lysosomal degradation of beta1 integrins by binding to the beta1-integrin tail. Nat Cell Biol. 2012 Jun;14(6):584-92
• All: 3 reference(s)