Unc5d^tm1.1Nuc
Targeted Allele Detail

Summary

• Symbol: Unc5d^tm1.1Nuc
• Name: unc-5 netrin receptor D; targeted mutation 1.1, Nuclear Dynamics group, Graduate School of Frontier Biosciences, Osaka University
• MGI ID: MGI:5523954
• Gene: Unc5d Location: Chr8:29136745-29709664 bp, - strand Genetic Position: Chr8, 16.47 cM
• Alliance: Unc5d^tm1.1Nuc page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:201425
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: (129 x C57BL/6J)F1

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: Exon 1 was replaced with a loxP-neo-loxP cassette. The floxed neo cassette was removed by cre excision. (J:201425)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Unc5d Mutation: 45 strains or lines available

References

• Original: J:201425 Zhu Y, et al., Dependence receptor UNC5D mediates nerve growth factor depletion-induced neuroblastoma regression. J Clin Invest. 2013 Jul 1;123(7):2935-47
• All: 1 reference(s)