Lbhtm1.2Kbri
Targeted Allele Detail
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Symbol: |
Lbhtm1.2Kbri |
Name: |
limb-bud and heart; targeted mutation 1.2, Karoline J Briegel |
MGI ID: |
MGI:5511022 |
Synonyms: |
Lbhdelta2 |
Gene: |
Lbh Location: Chr17:73225300-73248941 bp, + strand Genetic Position: Chr17, 44.73 cM, cytoband E2
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Alliance: |
Lbhtm1.2Kbri page
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Postnatal mammary gland defects in Lbhtm1.2Kbri/Lbhtm1.2Kbri mice
Show the 1 phenotype image(s) involving this allele.
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Germline Transmission: |
Earliest citation of germline transmission:
J:199325
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Parent Cell Line: |
W4 (ES Cell)
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Strain of Origin: |
129S6/SvEvTac
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Allele Type: |
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Targeted (Null/knockout) |
Mutations: |
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Insertion, Intragenic deletion
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Mutation details: A loxP site was inserted upstream of exon 2. An FRT- and loxP-flanked neomycin resistance cassette was inserted downstream of exon 2. Flp-mediated recombination removed the neomycin resistance cassette and left exon 2 floxed. Cre-mediated recombination removed exon 2. Western blot analysis confirmed the absence of protein expression in embryos.
(J:199325)
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Generation of the Lbhtm1.1Kbri and Lbhtm1.2Kbri alleles |
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View phenotypes and curated references for all genotypes (concatenated display).
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Carrying any Lbh Mutation: |
7 strains or lines available
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Original: |
J:199325 Lindley LE, et al., Generation of mice with a conditional Lbh null allele. Genesis. 2013 Jul;51(7):491-7 |
All: |
3 reference(s) |
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