Pcdhg^tm1.2Sch
Targeted Allele Detail

Summary

• Symbol: Pcdhg^tm1.2Sch
• Name: protocadherin gamma cluster; targeted mutation 1.2, Martin K Schwarz
• MGI ID: MGI:5504505
• Synonyms: gamma-pcdh^lox
• Gene: Pcdhg Location: unknown Genetic Position: Chr18, Syntenic

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:195283
• Parent Cell Line: R1 (ES Cell)
• Strain of Origin: (129X1/SvJ x 129S1/Sv)F1-Kitl⁺

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: A floxed PGK-neo cassette was inserted 417 bp downstream of the gammaC1 exon and an additional loxP site was inserted 1026 bp upstream. The selection cassette was removed by cre excision from properly targeted mice leaving the gammaC1 exon flanked by loxP sites. (J:195283)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Pcdhg Mutation: 12 strains or lines available

References

• Original: J:195283 Ledderose J, et al., Maturation of postnatally generated olfactory bulb granule cells depends on functional gamma-protocadherin expression. Sci Rep. 2013;3:1514
• All: 1 reference(s)