Tg(PER2*S662G)#Ljp
Transgene Detail

Summary

• Symbol: Tg(PER2*S662G)#Ljp
• Name: transgene insertion, Louis J Ptacek
• MGI ID: MGI:5494485
• Transgene: Tg(PER2*S662G)#Ljp Location: unknown
• Alliance: Tg(PER2*S662G)#Ljp page

Transgene origin

• Strain of Origin: C57BL/6

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Tg(PER2*S662G)#Ljp expresses 1 gene
  Transgene expresses:
  

  Organism

  Expressed Gene

  Homolog in Mouse

  Note

  human

  PER2 (8864)

  Per2	(MGI:1195265)

  Transgene codes for a protein with a serine to glycine mutation.

• Mutation details: The full-length sequence of the human PER2 gene carried in BAC RP11-139K17 was modified to change serine residue 662 to aspartic acid (S662G, AGT->GGT). (J:126404)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:194250 Shi G, et al., Dual roles of FBXL3 in the mammalian circadian feedback loops are important for period determination and robustness of the clock. Proc Natl Acad Sci U S A. 2013 Mar 19;110(12):4750-5
• All: 2 reference(s)