Ntn4^tm1Wjbr
Targeted Allele Detail

Summary

• Symbol: Ntn4^tm1Wjbr
• Name: netrin 4; targeted mutation 1, William Brunken
• MGI ID: MGI:5490629
• Gene: Ntn4 Location: Chr10:93476911-93581834 bp, + strand Genetic Position: Chr10, 48.59 cM, cytoband C3
• Alliance: Ntn4^tm1Wjbr page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:196758
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: A neomycin resistance cassette replaced 3.9 kb containing part of the first exon, the first intron and part of the second exon. Immunohistochemistry confirmed the absence of protein expression in the retina. (J:196758)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Ntn4 Mutation: 58 strains or lines available

References

• Original: J:196758 Li YN, et al., The expression and function of netrin-4 in murine ocular tissues. Exp Eye Res. 2012 Mar;96(1):24-35
• All: 2 reference(s)