Ptp4a3tm1.1Geh
Targeted Allele Detail
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Symbol: |
Ptp4a3tm1.1Geh |
Name: |
protein tyrosine phosphatase 4a3; targeted mutation 1.1, Gregg E Homanics |
MGI ID: |
MGI:5473867 |
Gene: |
Ptp4a3 Location: Chr15:73594991-73629075 bp, + strand Genetic Position: Chr15, 34.05 cM, cytoband E1
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Alliance: |
Ptp4a3tm1.1Geh page
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Allele Type: |
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Targeted (Null/knockout) |
Mutations: |
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Insertion, Intragenic deletion
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Mutation details: A loxP site was inserted upstream of exon 2. An FRT-flanked neo cassette with a 3' loxP site was inserted downstream of exon 2. Cre-mediated recombination removed exon 2. This allele lacks the neo cassette (removed by either flp- or cre-mediated recombination). Western blot analysis confirmed the absence of protein expression in the fetal heart, fetal intestine, adult heart, skeletal muscle, pancreas, lung, spleen, brain, thymus, colon and small intestine.
(J:194458)
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Details of the generation of the Ptp4a3tm1Geh and Ptp4a3tm1.1Geh alleles |
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View phenotypes and curated references for all genotypes (concatenated display).
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Carrying any Ptp4a3 Mutation: |
15 strains or lines available
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Original: |
J:194458 Zimmerman MW, et al., Targeted Deletion of the Metastasis-Associated Phosphatase Ptp4a3 (PRL-3) Suppresses Murine Colon Cancer. PLoS One. 2013;8(3):e58300 |
All: |
2 reference(s) |
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