Cited2^tm3.1Bha
Targeted Allele Detail

Summary

• Symbol: Cited2^tm3.1Bha
• Name: Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2; q targeted mutation 3.1, Shoumo Bhattacharya
• MGI ID: MGI:5472019
• Synonyms: Cited2^T166N
• Gene: Cited2 Location: Chr10:17598966-17601422 bp, + strand Genetic Position: Chr10, 7.18 cM, cytoband A2
• Alliance: Cited2^tm3.1Bha page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:192202
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129

Mutation description

Allele Type: Targeted (Humanized sequence) Mutations: Insertion, Nucleotide substitutions Mutation details: A C to A transversion results in the amino acid substitution of arginine for threonine at position 166 (T166N). Flp-mediated recombination removed the FRT-flanked neo cassette inserted downstream of the modification. (J:192202)

Generation of the Cited2^tm3.1Bha allele

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Cited2 Mutation: 24 strains or lines available

References

• Original: J:192202 Chen CM, et al., Functional significance of SRJ domain mutations in CITED2. PLoS One. 2012;7(10):e46256
• All: 1 reference(s)