Ndrg2^tm1.1Xzg
Targeted Allele Detail

Summary

• Symbol: Ndrg2^tm1.1Xzg
• Name: N-myc downstream regulated gene 2; targeted mutation 1.1, Xizhi Guo
• MGI ID: MGI:5441449
• Gene: Ndrg2 Location: Chr14:52142728-52151461 bp, - strand Genetic Position: Chr14, 26.72 cM
• Alliance: Ndrg2^tm1.1Xzg page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:187603
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129S/SvEv

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: Cre-mediated recombination removed the neo cassette and exons 2 through 6. Western blot analysis confirmed the absence of protein expression in E11.5 embryos. (J:187603)

Expression

In Mice Carrying this Mutation:	44 assay results
In Structures Affected by this Mutation:	3 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Ndrg2 Mutation: 26 strains or lines available

References

• Original: J:187603 Zhu H, et al., Ndrg2 regulates vertebral specification in differentiating somites. Dev Biol. 2012 Sep 15;369(2):308-18
• All: 5 reference(s)