Gt(ROSA)26Sortm1.1(Ctnnb1)Kem
Targeted Allele Detail
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Symbol: |
Gt(ROSA)26Sortm1.1(Ctnnb1)Kem |
Name: |
gene trap ROSA 26, Philippe Soriano; targeted mutation 1.1, Rolf Kemler |
MGI ID: |
MGI:5440174 |
Synonyms: |
ROSA26Beta |
Gene: |
Gt(ROSA)26Sor Location: Chr6:113044389-113054205 bp, - strand Genetic Position: Chr6, 52.73 cM
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Alliance: |
Gt(ROSA)26Sortm1.1(Ctnnb1)Kem page
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Germline Transmission: |
Earliest citation of germline transmission:
J:187739
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Parent Cell Line: |
W4 (ES Cell)
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Strain of Origin: |
129S6/SvEvTac
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Allele Type: |
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Targeted (Inserted expressed sequence) |
Mutation: |
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Insertion
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Gt(ROSA)26Sortm1.1(Ctnnb1)Kem expresses
1 gene
Knock-in expresses:
Organism |
Expressed Gene |
Note |
mouse |
Ctnnb1 (MGI:88276) |
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Mutation details: A splice acceptor site, floxed beta-geo stop cassette and a full length Ctnnb1 gene were inserted via homologous recombination. Cre mediated recombination removed the floxed beta-geo stop cassette.
(J:187739)
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View phenotypes and curated references for all genotypes (concatenated display).
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Carrying any Gt(ROSA)26Sor Mutation: |
942 strains or lines available
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Original: |
J:187739 Rudloff S, et al., Differential requirements for beta-catenin during mouse development. Development. 2012 Oct;139(20):3711-21 |
All: |
2 reference(s) |
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