Bcl11a^tm1Sbri
Targeted Allele Detail

Summary

• Symbol: Bcl11a^tm1Sbri
• Name: BCL11 transcription factor A; targeted mutation 1, Stefan Britsch
• MGI ID: MGI:5320880
• Synonyms: Bcl11a^flox
• Gene: Bcl11a Location: Chr11:24028056-24124123 bp, + strand Genetic Position: Chr11, 14.41 cM
• Alliance: Bcl11a^tm1Sbri page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:184011
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: A floxed neo cassette was inserted 3' of exon 1 and a loxP site was inserted 5' of exon 1 via homologous recombination. (J:184011)

Expression

In Structures Affected by this Mutation:

2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Bcl11a Mutation: 42 strains or lines available

References

• Original: J:184011 John A, et al., Bcl11a is required for neuronal morphogenesis and sensory circuit formation in dorsal spinal cord development. Development. 2012 May;139(10):1831-41
• All: 2 reference(s)