Becn1^tm1Ebr
Targeted Allele Detail

Summary

• Symbol: Becn1^tm1Ebr
• Name: beclin 1, autophagy related; targeted mutation 1, Edmund B Rucker III
• MGI ID: MGI:5308732
• Synonyms: Becn^fl
• Gene: Becn1 Location: Chr11:101179084-101193112 bp, - strand Genetic Position: Chr11, 64.58 cM, cytoband D
• Alliance: Becn1^tm1Ebr page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:180916
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• LoxP sites were inserted 5' and 3' of exons 1 and 2. (J:180916)

Disease models

Expression

In Structures Affected by this Mutation:

6 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Becn1 Mutation: 35 strains or lines available

References

• Original: J:180916 Gawriluk TR, et al., Autophagy is a cell survival program for female germ cells in the murine ovary. Reproduction. 2011 Jun;141(6):759-65
• All: 14 reference(s)