Egln3<tm1Vlcg> Targeted Allele Detail MGI Mouse (MGI:5304712)

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Egln3^tm1Vlcg
Targeted Allele Detail

Summary | Mutation origin | Mutation description | Phenotypes | Disease models | Find Mice (IMSR) | References

Summary

Symbol:	Egln3^tm1Vlcg
Name:	egl-9 family hypoxia-inducible factor 3; targeted mutation 1, Velocigene
MGI ID:	MGI:5304712
Synonyms:	Phd3^-
Gene:	Egln3 Location: Chr12:54225767-54250646 bp, - strand Genetic Position: Chr12, 22.9 cM
Alliance:	Egln3^tm1Vlcg page

Mutation
origin

Germline Transmission:	Earliest citation of germline transmission: J:179490
Parent Cell Line:	Not Specified (ES Cell)
Strain of Origin:	Not Specified

Mutation
description

Allele Type:		Targeted (Null/knockout)
Mutation:		Not Specified
		No details provided.

Phenotypes

View phenotypes and curated references for all genotypes (concatenated display).

Disease models

Find Mice (IMSR)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available Cell Lines: 0 lines available
Carrying any Egln3 Mutation:	24 strains or lines available

References

Original:	J:179490 Moslehi J, et al., Loss of hypoxia-inducible factor prolyl hydroxylase activity in cardiomyocytes phenocopies ischemic cardiomyopathy. Circulation. 2010 Sep 7;122(10):1004-16
All:	4 reference(s)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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