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Dppa4tm1Yam
Targeted Allele Detail
Summary
Symbol: Dppa4tm1Yam
Name: developmental pluripotency associated 4; targeted mutation 1, Shinya Yamanaka
MGI ID: MGI:5298638
Synonyms: 15-1CT
Gene: Dppa4  Location: Chr16:48104096-48114600 bp, + strand  Genetic Position: Chr16, 30.75 cM
Alliance: Dppa4tm1Yam page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:178324
Parent Cell Line:  RF8 (ES Cell)
Strain of Origin:  129S4/SvJae
Mutation
description
Allele Type:    Targeted (Conditional ready, No functional change)
Mutation:    Insertion
 
Mutation detailsA floxed neo cassette was inserted into intron 1 and a loxP site was inserted after the last exon via homologous recombination. This allele was created in tandem with Dppa2tm1Yam. These alleles are in cis to each other. (J:178324)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Dppa4 Mutation:  41 strains or lines available
References
Original:  J:178324 Nakamura T, et al., Essential roles of ECAT15-2/Dppa2 in functional lung development. Mol Cell Biol. 2011 Nov;31(21):4366-78
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
01/24/2023
MGI 6.22
The Jackson Laboratory