About   Help   FAQ
Targeted Allele Detail
Symbol: Taar1tm1Mmil
Name: trace amine-associated receptor 1; targeted mutation 1, Mark J Millan
MGI ID: MGI:5297915
Gene: Taar1  Location: Chr10:23796304-23797302 bp, + strand  Genetic Position: Chr10, 11.39 cM, cytoband A3
Alliance: Taar1tm1Mmil page
Germline Transmission:  Earliest citation of germline transmission: J:178061
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  129S2/SvPas
Allele Type:    Targeted (Null/knockout, Reporter)
Mutations:    Insertion, Intragenic deletion
Mutation detailsMost of the coding sequence was replaced by an IRES lacZ gene and a floxed neo cassette. Western blot analysis confirmed the absence of transcript expression. (J:178061)
View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Taar1 Mutation:  32 strains or lines available
Original:  J:178061 Di Cara B, et al., Genetic Deletion of Trace Amine 1 Receptors Reveals Their Role in Auto-Inhibiting the Actions of Ecstasy (MDMA). J Neurosci. 2011 Nov 23;31(47):16928-16940
All:  4 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
MGI 6.13
The Jackson Laboratory