Tg(AR*20Q)C9BAls
Transgene Detail

Summary

• Symbol: Tg(AR*20Q)C9BAls
• Name: transgene insertion C9B, Albert La Spada
• MGI ID: MGI:5000267
• Synonyms: AR20, AR YAC CAG20
• Transgene: Tg(AR*20Q)C9BAls Location: unknown
• Alliance: Tg(AR*20Q)C9BAls page

Transgene origin

• Germline Transmission: Earliest citation of germline transmission: J:89772
• Parent Cell Line: R1 (ES Cell)
• Strain of Origin: (129X1/SvJ x 129S1/Sv)F1-Kitl⁺

Transgene description

• Transgene Type: Transgenic (Humanized sequence, Inserted expressed sequence)
• Mutation: Insertion
• Tg(AR*20Q)C9BAls expresses 1 gene
  Transgene expresses:
  

  Organism

  Expressed Gene

  Homolog in Mouse

  Note

  human

  AR (367)

  Ar	(MGI:88064)

• Mutation details: The transgene contains a human YAC in which the CAG repeat contains 20 repeats (20Q). Lines C3A and C9B were generated. (J:89772)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:89772 Sopher BL, et al., Androgen receptor YAC transgenic mice recapitulate SBMA motor neuronopathy and implicate VEGF164 in the motor neuron degeneration. Neuron. 2004 Mar 4;41(5):687-99
• All: 2 reference(s)