Synj2^mozart
Chemically induced Allele Detail

Summary

• Symbol: Synj2^mozart
• Name: synaptojanin 2; mozart
• MGI ID: MGI:4999986
• Synonyms: Synj2^N538K
• Gene: Synj2 Location: Chr17:5991555-6094565 bp, + strand Genetic Position: Chr17, 3.59 cM, cytoband A2-A3.1
• Alliance: Synj2^mozart page

Synj2^mozart/Synj2^mozart cochleae exhibit degeneration

Show the 2 phenotype image(s) involving this allele.

Mutation origin

• Strain of Origin: C57BL/6

Mutation description

• Allele Type: Chemically induced (ENU)
• Mutation: Single point mutation
• Mutation details: ENU induced a T to A mutation at nucleotide 1641 resulting in an asparagine to lysine substitution in the highly conserved catalytic 5-phosphatase domain of the enzyme. (J:171701)

Expression

In Structures Affected by this Mutation:

2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Synj2 Mutation: 74 strains or lines available

References

• Original: J:171701 Manji SS, et al., A mutation in synaptojanin 2 causes progressive hearing loss in the ENU-mutagenised mouse strain Mozart. PLoS One. 2011;6(3):e17607
• All: 1 reference(s)