Ppp2catm1.1Nju
Targeted Allele Detail
|
Symbol: |
Ppp2catm1.1Nju |
Name: |
protein phosphatase 2 (formerly 2A), catalytic subunit, alpha isoform; targeted mutation 1.1, Model Animal Research Center of Nanjing University |
MGI ID: |
MGI:4950915 |
Synonyms: |
PP2Acalphaflox, Ppp2cafl |
Gene: |
Ppp2ca Location: Chr11:51989651-52013576 bp, + strand Genetic Position: Chr11, 31.86 cM
|
Alliance: |
Ppp2catm1.1Nju page
|
|
Germline Transmission: |
Earliest citation of germline transmission:
J:171578
|
Parent Cell Line: |
W4 (ES Cell)
|
Strain of Origin: |
129S6/SvEvTac
|
|
Allele Type: |
|
Targeted (Conditional ready, No functional change) |
Mutation: |
|
Insertion
|
|
|
Mutation details: An FRT flanked selection cassette and loxP site were inserted upstream of exon 3 and a loxP site was inserted downstream of exon 5 via homologous recombination. Flp mediated recombination removed the selection cassette.
(J:171578, J:184036)
|
|
|
View phenotypes and curated references for all genotypes (concatenated display).
|
|
Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
|
Carrying any Ppp2ca Mutation: |
25 strains or lines available
|
|
Original: |
J:171578 Chen W, et al., Protein Phosphatase 2A Catalytic Subunit alpha (PP2Acalpha) Maintains Survival of Committed Erythroid Cells in Fetal Liver Erythropoiesis through the STAT5 Pathway. Am J Pathol. 2011 May;178(5):2333-43 |
All: |
9 reference(s) |
|