Tg(Eno2-Lepr)3Chua
Transgene Detail

Summary

• Symbol: Tg(Eno2-Lepr)3Chua
• Name: transgene insertion 3, Streamson Chua
• MGI ID: MGI:4940292
• Synonyms: NseLEPR-B, NSE-LEPR_B, NSE-Rb
• Transgene: Tg(Eno2-Lepr)3Chua Location: unknown
• Alliance: Tg(Eno2-Lepr)3Chua page

Transgene origin

• Strain of Origin: (C57BL/6J x CBA)F2

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Tg(Eno2-Lepr)3Chua expresses 1 gene
  Transgene expresses:
  

  Organism	Expressed Gene	Note
  mouse	Lepr (MGI:104993)

• Mutation details: A 1.8 kb rat neuron-specific enolase (NSE) promoter fragment drives expression of a full-length cDNA encoding the "B" isoform of mouse Lepr. (J:67220)

Tumor Data

List all tumor models in MMHCdb carrying Tg(Eno2-Lepr)3Chua

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:67220 Kowalski TJ, et al., Transgenic complementation of leptin-receptor deficiency. I. Rescue of the obesity/diabetes phenotype of LEPR-null mice expressing a LEPR-B transgene. Diabetes. 2001 Feb;50(2):425-35
• All: 4 reference(s)