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Gt(ROSA)26Sortm1(FLII)Hdc
Targeted Allele Detail
Summary
Symbol: Gt(ROSA)26Sortm1(FLII)Hdc
Name: gene trap ROSA 26, Philippe Soriano; targeted mutation 1, Hugh D Campbell
MGI ID: MGI:4939369
Synonyms: R26R(FLII), RRF
Gene: Gt(ROSA)26Sor  Location: Chr6:113044389-113054205 bp, - strand  Genetic Position: Chr6, 52.73 cM
Alliance: Gt(ROSA)26Sortm1(FLII)Hdc page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:168970
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  BALB/c
Mutation
description
Allele Type:    Targeted (Conditional ready, Humanized sequence, Inserted expressed sequence, No functional change)
Mutation:    Insertion
 
Gt(ROSA)26Sortm1(FLII)Hdc expresses 1 gene
 
Mutation detailsThe full length human FLII cDNA (4.1 Kb) replaced YFP in the vector pROSA26PA. The genomic ROSA26 locus (MMu 6) is therefore modified to contain a floxed trimer of the SV40 polyadenylation signal (tpA) upstream of the FLII cDNA. (J:168970)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Gt(ROSA)26Sor Mutation:  942 strains or lines available
References
Original:  J:168970 Thomsen N, et al., Mouse strains for the ubiquitous or conditional overexpression of the Flii gene. Genesis. 2011 Aug;49(8):681-8
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/23/2024
MGI 6.23
The Jackson Laboratory