Gt(ROSA)26Sortm1(FLII)Hdc
Targeted Allele Detail
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Symbol: |
Gt(ROSA)26Sortm1(FLII)Hdc |
Name: |
gene trap ROSA 26, Philippe Soriano; targeted mutation 1, Hugh D Campbell |
MGI ID: |
MGI:4939369 |
Synonyms: |
R26R(FLII), RRF |
Gene: |
Gt(ROSA)26Sor Location: Chr6:113044389-113054205 bp, - strand Genetic Position: Chr6, 52.73 cM
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Alliance: |
Gt(ROSA)26Sortm1(FLII)Hdc page
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Germline Transmission: |
Earliest citation of germline transmission:
J:168970
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Parent Cell Line: |
Not Specified (ES Cell)
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Strain of Origin: |
BALB/c
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Allele Type: |
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Targeted (Conditional ready, Humanized sequence, Inserted expressed sequence, No functional change) |
Mutation: |
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Insertion
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Gt(ROSA)26Sortm1(FLII)Hdc expresses
1 gene
Knock-in expresses:
Organism |
Expressed Gene |
Homolog in Mouse |
Note |
human |
FLII (2314) |
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Mutation details: The full length human FLII cDNA (4.1 Kb) replaced YFP in the vector pROSA26PA. The genomic ROSA26 locus (MMu 6) is therefore modified to contain a floxed trimer of the SV40 polyadenylation signal (tpA) upstream of the FLII cDNA.
(J:168970)
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Original: |
J:168970 Thomsen N, et al., Mouse strains for the ubiquitous or conditional overexpression of the Flii gene. Genesis. 2011 Aug;49(8):681-8 |
All: |
1 reference(s) |
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