Pnpt1^tm1Teit
Targeted Allele Detail

Summary

• Symbol: Pnpt1^tm1Teit
• Name: polyribonucleotide nucleotidyltransferase 1; targeted mutation 1, Micheal Teitell
• MGI ID: MGI:4882055
• Synonyms: Pnpt1^neo-flox
• Gene: Pnpt1 Location: Chr11:29080744-29111828 bp, + strand Genetic Position: Chr11, 16.46 cM, cytoband A4
• Alliance: Pnpt1^tm1Teit page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:167932
• Parent Cell Line: Bruce 4 (ES Cell)
• Strain of Origin: B6.Cg-Thy1^a

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: A loxP site was inserted upstream of exon 2, and a neo cassette with a 3' loxP site was inserted downstream of exon 2. (J:167932)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Pnpt1 Mutation: 40 strains or lines available

References

• Original: J:167932 Wang G, et al., PNPASE regulates RNA import into mitochondria. Cell. 2010 Aug 6;142(3):456-67
• All: 3 reference(s)