Tyr^m3Btlr
Chemically induced Allele Detail

Summary

• Symbol: Tyr^m3Btlr
• Name: tyrosinase; mutation 3, Bruce Beutler
• MGI ID: MGI:4868367
• Synonyms: siamese, Tyr^H420R
• Gene: Tyr Location: Chr7:87073979-87142637 bp, - strand Genetic Position: Chr7, 49.01 cM
• Alliance: Tyr^m3Btlr page

Mutation origin

• Strain of Origin: C57BL/6J
• Project Collection: Beutler Mutagenetix

Mutation description

• Allele Type: Chemically induced (ENU)
• Mutation: Single point mutation
• Mutation details: A to G transition at 94586554 bp on Chromosome 7. Position 1320 of the Tyr transcript using Genbank record NM_011661, in exon 4 of 5 total exons. Results in a histidine to arginine substitution at amino acid 420 of the encoded protein. (J:167507)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Tyr Mutation: 375 strains or lines available

References

• Original: J:167507 Beutler B, Direct Data Submission 2011/01/14. MGI Direct Data Submission. 2011
• All: 1 reference(s)