Adam10^tm1Beni
Targeted Allele Detail

Summary

• Symbol: Adam10^tm1Beni
• Name: a disintegrin and metallopeptidase domain 10; targeted mutation 1, Bernhard Nieswandt
• MGI ID: MGI:4839221
• Synonyms: Adam10^fl
• Gene: Adam10 Location: Chr9:70586279-70687511 bp, + strand Genetic Position: Chr9, 39.53 cM
• Alliance: Adam10^tm1Beni page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:165863
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129/Sv

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: An FRT-flanked neo with a 5' loxP site was inserted upsteam of exon 2 and an additional loxP site was inserted downstream of exon 2. (J:165863)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Adam10 Mutation: 37 strains or lines available

References

• Original: J:165863 Bender M, et al., Differentially regulated GPVI ectodomain shedding by multiple platelet-expressed proteinases. Blood. 2010 Oct 28;116(17):3347-55
• All: 1 reference(s)