Wdr77^tm2Zwan
Targeted Allele Detail

Summary

• Symbol: Wdr77^tm2Zwan
• Name: WD repeat domain 77; targeted mutation 2, Zhengxin Wang
• MGI ID: MGI:4821121
• Synonyms: p44/WDR77^loxP
• Gene: Wdr77 Location: Chr3:105866814-105877076 bp, + strand Genetic Position: Chr3, 46.46 cM
• Alliance: Wdr77^tm2Zwan page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:162922
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: A loxP site was introduced into intro 1 and a floxed neo cassette was introduced into intron 5 via homologous recombination. (J:162922)

Expression

In Structures Affected by this Mutation:

6 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Wdr77 Mutation: 17 strains or lines available

References

• Original: J:162922 Gao S, et al., Altered differentiation and proliferation of prostate epithelium in mice lacking the androgen receptor cofactor p44/WDR77. Endocrinology. 2010 Aug;151(8):3941-53
• All: 3 reference(s)