Fbxl5^L5Jcs32
Chemically induced Allele Detail

Summary

• Symbol: Fbxl5^L5Jcs32
• Name: F-box and leucine-rich repeat protein 5; lethal 5 John C Schimenti 32
• MGI ID: MGI:4458019
• Gene: Fbxl5 Location: Chr5:43901958-43939529 bp, - strand Genetic Position: Chr5, 23.81 cM
• Alliance: Fbxl5^L5Jcs32 page

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Chemically induced (ENU)
• Mutation: Single point mutation
• Mutation details: The mutation corresponds to a T to A transition in exon 3, that results in the replacement of methionine by lysine at amino acid position 127 of the protein. (J:94077)
• Inheritance: Recessive

Expression

In Structures Affected by this Mutation:

2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Fbxl5 Mutation: 45 strains or lines available

References

• Original: J:100332 Wilson L, et al., Random mutagenesis of proximal mouse chromosome 5 uncovers predominantly embryonic lethal mutations. Genome Res. 2005 Aug;15(8):1095-105
• All: 3 reference(s)