Pkm^r
Spontaneous Allele Detail

Summary

• Symbol: Pkm^r
• Name: pyruvate kinase, muscle; reduced activity
• MGI ID: MGI:4455158
• Synonyms: Pk-3^r
• Gene: Pkm Location: Chr9:59563859-59586655 bp, + strand Genetic Position: Chr9, 32.03 cM
• Alliance: Pkm^r page

Mutation origin

• Strain of Origin: C57BL/6

Mutation description

• Allele Type: Spontaneous
• Mutation: Undefined
• Mutation details: A spontaneous allele was identified by electrophoretic assay. Activity levels are reduced 50% in the heart and kidney of heterozygous mice.

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Pkm Mutation: 75 strains or lines available

References

• Original: J:6558 Johnson FM, et al., A variation in mouse kidney pyruvate kinase activity determined by a mutant gene on chromosome 9. Genet Res. 1981 Apr;37(2):123-31
• All: 3 reference(s)