Lepr^m4Btlr
Chemically induced Allele Detail

Summary

• Symbol: Lepr^m4Btlr
• Name: leptin receptor; mutation 4, Bruce Beutler
• MGI ID: MGI:4442910
• Synonyms: Odd
• Gene: Lepr Location: Chr4:101574601-101672549 bp, + strand Genetic Position: Chr4, 46.96 cM
• Alliance: Lepr^m4Btlr page

Mutation origin

• Strain of Origin: C57BL/6J
• Project Collection: Beutler Mutagenetix

Mutation description

• Allele Type: Chemically induced (ENU)
• Mutation: Single point mutation
• Mutation details: The mutation comprises a G to T transversion in the splice donor site of intron 2, five nucleotides from the previous exon. (J:159354)
• Inheritance: Not Specified

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Lepr Mutation: 121 strains or lines available

References

• Original: J:159354 Huang H, et al., Odd is an allele of Lepr and causes excessive body weight. MGI Direct Data Submission. 2010
• All: 1 reference(s)