Upk1b^tm1Pzg
Targeted Allele Detail

Summary

• Symbol: Upk1b^tm1Pzg
• Name: uroplakin 1B; targeted mutation 1, Pumin Zhang
• MGI ID: MGI:4441453
• Synonyms: Upk1b-RFP, Upk1b^tm1Zhang
• Gene: Upk1b Location: Chr16:38593544-38620565 bp, - strand Genetic Position: Chr16, 26.87 cM, cytoband B5-C2
• Alliance: Upk1b^tm1Pzg page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:159099
• Parent Cell Line: E14TG2a.4 (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutation: Insertion
• Mutation details: A targeting vector containing the Red Fluorescent Protein (RFP) gene followed, in reverse orientation, by two copies of a loxP and frt site-flanked kanamycin and neomycin resistance cassette (loxP-pA-frt-Kan&Neo-frt-loxP) was inserted into the first coding exon of the endogenous gene immediately following the ATG translation initiation codon. Red fluorescent signal is detected in the kidney and gonads of E15.5 heterozygous mutant embryos; fluorescence in the urogenital system mimics the expression pattern of the endogenous gene. (J:159099)
• Inheritance: Not Specified

Expression

In Mice Carrying this Mutation:

2 assay results 1 RNA-Seq or microarray experiment(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Upk1b Mutation: 17 strains or lines available

References

• Original: J:159099 McMahon A, et al., Summary of mouse strains characterized by GUDMAP consortium. Unpublished. 2010
• All: 5 reference(s)