Edn2^tm1.1Nat
Targeted Allele Detail

Summary

• Symbol: Edn2^tm1.1Nat
• Name: endothelin 2; targeted mutation 1.1, Jeremy Nathans
• MGI ID: MGI:4438396
• Synonyms: ET-2^fl, ET-2^flox
• Gene: Edn2 Location: Chr4:120018403-120024557 bp, + strand Genetic Position: Chr4, 55.77 cM
• Alliance: Edn2^tm1.1Nat page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:158269
• Parent Cell Line: R1 (ES Cell)
• Strain of Origin: (129X1/SvJ x 129S1/Sv)F1-Kitl⁺

Mutation description

Allele Type: Targeted (Conditional ready, No functional change) Mutation: Insertion Mutation details: The second exon of the targeted gene was flanked by two LoxP sites. Adjacent to the second LoxP site is an Frt site left over after the excision of the PGK-neomycin selectable marker. (J:158269)

Generation of the Edn2^tm1.1Nat allele

Expression

In Structures Affected by this Mutation:

6 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Edn2 Mutation: 14 strains or lines available

References

• Original: J:158269 Nathans J, Direct data submission for Edn2^tm1Nat. MGI Direct Data Submission. 2010
• All: 4 reference(s)