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Trpm1tm1Tfur
Targeted Allele Detail
Summary
Symbol: Trpm1tm1Tfur
Name: transient receptor potential cation channel, subfamily M, member 1; targeted mutation 1, Takahisa Furukawa
MGI ID: MGI:4421441
Gene: Trpm1  Location: Chr7:63803583-63919523 bp, + strand  Genetic Position: Chr7, Syntenic
Alliance: Trpm1tm1Tfur page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:156502
Parent Cell Line:  TC1/TC-1 (ES Cell)
Strain of Origin:  129S6/SvEvTac
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsExons 4-6 were replaced with a neo cassette. Northern blot verified no substantial transcript in retinas from homozygous mice. (J:156502)
Generation of the Trpm1tm1Tfur allele
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 2 strains available      Cell Lines: 0 lines available
Carrying any Trpm1 Mutation:  101 strains or lines available
References
Original:  J:156502 Koike C, et al., TRPM1 is a component of the retinal ON bipolar cell transduction channel in the mGluR6 cascade. Proc Natl Acad Sci U S A. 2010 Jan 5;107(1):332-7
All:  5 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/07/2024
MGI 6.23
The Jackson Laboratory