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Targeted Allele Detail
Symbol: Trpm1tm1Tfur
Name: transient receptor potential cation channel, subfamily M, member 1; targeted mutation 1, Takahisa Furukawa
MGI ID: MGI:4421441
Gene: Trpm1  Location: Chr7:63803583-63919523 bp, + strand  Genetic Position: Chr7, Syntenic
Alliance: Trpm1tm1Tfur page
Germline Transmission:  Earliest citation of germline transmission: J:156502
Parent Cell Line:  TC1/TC-1 (ES Cell)
Strain of Origin:  129S6/SvEvTac
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
Mutation detailsExons 4-6 were replaced with a neo cassette. Northern blot verified no substantial transcript in retinas from homozygous mice. (J:156502)
Generation of the Trpm1tm1Tfur allele
View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 2 strains available      Cell Lines: 0 lines available
Carrying any Trpm1 Mutation:  101 strains or lines available
Original:  J:156502 Koike C, et al., TRPM1 is a component of the retinal ON bipolar cell transduction channel in the mGluR6 cascade. Proc Natl Acad Sci U S A. 2010 Jan 5;107(1):332-7
All:  5 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
MGI 6.23
The Jackson Laboratory